Comfrey Leaf

Comfrey Leaf

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Traditionally Used for

  • Back pain. Applying a comfrey extract ointment to the affected area for 5 days seems to decrease lower or upper back pain.

  • Osteoarthritis. Applying a comfrey extract ointment to the affected area for 3 weeks or applying a specific cream containing comfrey extract, tannic acid, Aloe vera gel, eucalyptus oil, and frankincense oil to the affected are for 6-12 weeks seems to decrease pain in people with knee osteoarthritis.

  • Sprains. 

  • Bruises.

  • Abnormally heavy bleeding during menstrual periods (menorrhagia).

  • Blood in the urine (hematuria).

  • Cancer.

  • Chest pain (angina).

  • Cough.

  • Diarrhea.

  • Fractures.

  • Gout.

  • Gum disease (gingivitis).

  • Hemorrhoids.

  • Leg sores caused by weak blood circulation (venous leg ulcer).

  • Muscle soreness.

  • Rheumatoid arthritis.

  • Sore throat (pharyngitis).

  • Stomach ulcers.

  • Swelling (inflammation) of the main airways in the lungs (bronchitis).

  • Swelling (inflammation) of the stomach (gastritis).

  • Tuberculosis.

  • Varicose veins.

  • Wound healing.



Pregnancy and breast-feeding: Comfrey is LIKELY UNSAFE to take by mouth or apply to the skin if you are pregnant or breast-feeding. In addition to causing liver damage and possibly cancer, the PAs in comfrey might also cause birth defects. Even topical use is unwise, since the PAs can be absorbed through the skin.

Broken or damaged skin: Don't apply comfrey to broken or damaged skin. Doing so might expose you to large amounts of the chemicals in comfrey that can cause liver damage and other serious health effects.

Liver disease: There is a concern that comfrey might make liver disease worse. Don't use comfrey if you have any problems with your liver.

Major Interaction!

Do not take this combination:

           Medications that can harm the liver (Hepatotoxic drugs) interacts with COMFREY

Comfrey might harm the liver. Taking comfrey along with medication that might also harm the liver can increase the risk of liver damage. Do not take comfrey if you are taking a medication that can harm the liver.<br><nb>Some medications that can harm the liver include acetaminophen (Tylenol and others), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporanox), erythromycin (Erythrocin, Ilosone, others), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), and many others.

Medications that increase the breakdown of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inducers) interacts with COMFREY

Comfrey is broken down by the liver. Some chemicals that form when the liver breaks down comfrey can be harmful. Medications that cause the liver to break down comfrey might enhance the toxic effects of chemicals contained in comfrey.<br><nb>Some of these medicines include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin)

For educational purposes only. This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options.